malthus, on Apr 5 2009, 03:52 PM, said:
I'm presently at 2 hours and still running. There's definitely an exponential slowdown in the scan as time goes on - the longer into the scan the slower it takes. It's current scan rate is approximately 3 files per second. Something is not right here.

Disregarding the possibility that an infection itself may be causing the computer to become progressively slower, start with simple stuff.
How much RAM do you have?
What size is/are the hard drive(s)?
What is your CPU speed?
What is the architecture?
How fast do your hard drives spin?
On this computer a "full scan" takes me about an hour-and-a-half (not just the first time):
2 GB RAM
AMD Athlon XP 2400+ 2.0 GHz
40 GB 1st hard disk drive, 5400 rpm
32-bit
120 BG second hard disk drive, 7200 rpm
On this one, in spite of the large disks, it only takes about 20 minutes!
4 GB RAM (incorrectly identified in another post as 8!)
AMD Athlon 64 X2 Dual Core 5200+ 2.71 GHz
64-bit (but running older 32-bit XP)
300 GB 1st hard disk (210 GB not used for Windows, so effectively 290), 7200 rpm
500 GB 2nd hard disk, 7200 rpm