Thank you Maurice Naggar for your response and thank you for the online resources. Virus total does not come up with any indication of an infection. Virscan comes up with an infection of Trojan: JS/Medfos.B under Microsoft only and nothing else. While I am no expert, and while ChromeUpdateManager may be a legitimate extension, I feel it is not. Considering the only results for a search of "ChromeUpdateManager" comes up with threads about viruses and the logo of the extension appears very inconsistant compared to Google's other products, I believe this is something to be concerned about. And to give you a little background, I have been dealing with this for a few days now. I did not switch out Microsoft SE for Nod32 on a whim, I did it after considerable research and various basic procedures in dealing with viruses. In my research I came up with this thread: http://social.technet.microsoft.com/Forums/en-US/FCSNext/thread/c28665c4-8786-4549-9b51-3d513474b3e0, which is the exact same issue I have been having. It appears that some solutions have been to reinstall Java and to update the virus definitions. I do not have Java installed and I have updated virus definitions beyond the version stated in this thread and I still have the problem. So, in summary, a Google search gives me no indication that chromeupdate.crx and ChromeUpdateManager extension are legitimate. And, there IS an indication that they may be ILLEGITIMATE from the results of a Google search, Microsoft SE, and Virscan.org (however Microsoft is the only source that claims this is a trojan). I am not incredibly concerned with this, it is mostly annoying. But it makes me wonder how this file appeared out of no where, why the extension appeared out of no where and why it looks out of place (again neither the extension or the file are on other computers with Chrome installed), and why Microsoft seems to claim this as a trojan while no other AV does.