I am getting the same runtime error when I try to install version 1.45 on Win2K machine. Runtime error (at-1:0): Cannot import dll:\C\Documen~1\user\Locals~1\temp\ER8UL.tmp\mbam.dll. Each time I tried to install it the follow on error message changed but the runtime error remained the same. I also ran the clean.exe after uninstalling mbam and it still gives me the Run time error code. No other programs are malfunctioning. The last update I did on Malwarebytes was yesterday 03/28/10 and I had no problem. When I checked the update for today 03/29/10 I got the runtime error. Really puzzled by this, any help would be greatly appreciated. Miketerr