I had disabled Malwarebyte's Protection Module when AVG 2011 was determined to be in conflict with it. I updated to AVG 2011 to 1170 and after rebooting, and running for a few days, I updated Malwarebyte's to v1.50. Since the previous settings were retained (Protection Module NOT enabled), everything worked fine (Updates, Scans, etc.) Then I enabled the Protection Module and everything seemed fine until I did a reboot. After about 3 minutes, Windows Explorer hung IE; the mouse went "busy", the keyboard was locked out, and nothing updated in the System Tray (Network icon, Process Explorer icon, etc.). The only workaround was to power off/on and quickly open Task Manager or Process Explorer and kill AVG's Resident Shield (this kicked off a lot of activity in Process Explorer with many different processes starting again but the system returned to normal with no problems). AVG Resident Shield can then be permanently disabled on the AVG main window. -OR- As soon as Malwarebyte's Tray icon appears in the System Tray, right click on it and uncheck "Enable Protection", uncheck "Windows Startup" option and then click "Exit" and respond OK to the "Are you sure..." popup before the PC hangs. After that, the reboots were successful. AVG 8.5 and AVG 9.0 were compatible with all versions of Malwarebyte's Protection Module running. Too bad. So as of now, the User must decide whether to disable AVG's Resident Shield or Malwarebyte's Protection Module.